KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2A
All Species:
17.58
Human Site:
T9
Identified Species:
29.74
UniProt:
Q9BY44
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BY44
NP_114414.2
585
64990
T9
A
P
S
T
P
L
L
T
V
R
G
S
E
G
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108004
580
64436
T9
A
P
S
T
P
L
L
T
V
R
G
S
E
G
L
Dog
Lupus familis
XP_534306
585
65159
T9
A
P
S
T
P
L
L
T
V
R
G
S
E
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJW6
581
64385
T9
A
P
S
T
P
L
L
T
V
R
G
S
E
G
L
Rat
Rattus norvegicus
NP_001102809
541
60196
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507598
493
54394
Chicken
Gallus gallus
Q5ZKC1
586
64485
A9
A
P
P
A
P
L
L
A
V
R
G
S
E
G
L
Frog
Xenopus laevis
Q7ZY11
582
64798
S9
A
P
P
M
P
L
L
S
V
R
G
S
D
G
I
Zebra Danio
Brachydanio rerio
Q4QRJ7
580
64206
A9
A
P
P
T
P
H
L
A
V
R
G
S
D
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNX8
638
70052
E21
I
R
S
S
V
A
V
E
L
W
S
S
A
G
S
Honey Bee
Apis mellifera
XP_625143
577
65273
A9
A
L
N
V
P
C
V
A
V
R
G
S
I
G
I
Nematode Worm
Caenorhab. elegans
Q19052
570
64001
R10
D
N
L
V
Y
A
V
R
S
S
E
G
F
Y
L
Sea Urchin
Strong. purpuratus
XP_001186352
299
33040
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53235
642
71286
E14
L
K
T
S
Q
D
I
E
L
F
Q
S
Y
P
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
96
N.A.
92.8
82.5
N.A.
74.5
84.4
74.8
69.5
N.A.
39
43.9
35.7
29.2
Protein Similarity:
100
N.A.
98.2
98.2
N.A.
95.5
87
N.A.
79.4
91.6
86.5
81.5
N.A.
56.5
61.3
54.8
40
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
0
80
66.6
66.6
N.A.
20
46.6
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
0
N.A.
0
80
86.6
73.3
N.A.
40
66.6
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
0
8
0
15
0
22
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
0
0
0
15
0
0
% D
% Glu:
0
0
0
0
0
0
0
15
0
0
8
0
36
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
58
8
0
65
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
8
0
15
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
8
0
0
43
50
0
15
0
0
0
0
0
43
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
50
22
0
58
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
58
0
0
0
0
0
% R
% Ser:
0
0
36
15
0
0
0
8
8
8
8
72
0
0
8
% S
% Thr:
0
0
8
36
0
0
0
29
0
0
0
0
0
0
15
% T
% Val:
0
0
0
15
8
0
22
0
58
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _